MEBO was smeared successively onto the wounds at a thickness of 1 mm twice daily with a sterile gloved finger.

The NICE British National Formulary (BNF) site is only available to users in the UK (England, Scotland, Wales and Northern Ireland).However, in the present study, a significant difference in terms of pain reduction (VAS) in favor of group I was encountered when compared to group II on day 3. Without improvement was defined as no change in ulcer size compared with the baseline ulcer tracing. The required sample size of this study was estimated to be 72 subjects, 36 in each group with α = 0. Vestibular deepening heals by secondary intention, which shows a similar pattern to palatal wound-healing. At the end of 2 months, the ulcers were examined blindly and assessed as “Completely Healed,” “Partially Healed,” “Without Improvement,” or “Worsening.

Management of the acute partial-thickness burned hand; moist exposed burn ointment or silver sulphadiazine cream both combined with a polyethylene bag. For intergroup comparison between MEBO and HA, no significant difference in terms of VAS score was present on day 2 and day 4, which is consistent with the results of the previous study [ 16], where no significant difference could be found on day 2 and day 4. Thirty-nine subjects were selected from the outpatient clinic, Oral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, between March 2019 and September 2020.

edu/twiki/bin/view/Main/PowerSampleSize) and approved by medical biostatistics unit, Cairo University, in October 2018. On day 0 and day 3, the highest mean value was recorded in group II; however, the difference between groups did not reach the level of statistical significance. However, there is currently limited evidence to evaluate the efficacy and safety of MEBO for treating pressure ulcers. The pain reduction and rapid healing in intervention groups (group I and II) are possibly due to the anti-inflammatory and antioxidant effects of their main components as b-sitosterol for MEBO and sodium hyaluronate for HA gel rather than rapid epithelialization.